ANAHEIM — Jered Weaver and two relievers combined to pitch a three-hitter and Mike Napoli hit a tiebreaking sacrifice fly in the eighth, leading the Los Angeles Angels to a 2-0 victory over the Chicago White Sox on Tuesday night.

A.J. Pierzynski's leadoff single in the fifth was the only hit off Weaver, who pitched seven innings. The right-hander from Simi Valley struck out six and walked one, coming out of the game after 109 pitches. He was 1-4 with a 7.02 ERA in his previous six starts after pitching seven scoreless innings of three-hit ball in a 2-1 win over Texas on April 5.

Chicago starter John Danks had a hard-luck no-decision, although he had to work hard for it. Pitching against the Angels for the first time in his career, he scattered seven hits and two walks over 613 innings, struck out five and never retired the side in order.

Danks departed with one out and the bases loaded in the seventh after walking Gary Matthews Jr. with his 99th and final pitch. Octavio Dotel struck out Erick Aybar and Vladimir Guerrero to escape the jam.

But Dotel (1-2) gave up a leadoff single in the eighth to Hunter, who took third on Garret Anderson's single against Matt Thornton and scored on Napoli's flyout to center. Two batters later, Robb Quinlan drove in the second run with a single against Scott Linebrink.

Scot Shields (2-0) pitched one inning for the win and Francisco Rodriguez got three outs for his major league-leading 16th save.

The Angels stranded a runner in scoring position in four of the first five innings. Hunter grounded out with a man on third base to end the first, Guerrero hit into a double play to end the third, Casey Kotchman flied out to end the fourth, and Aybar grounded out to end the fifth.

Chicago manager Ozzie Guillen flip-flopped Paul Konerko and Jermaine Dye in his lineup, dropping the slumping Konerko to fifth and putting Dye in the cleanup spot for the fourth time this season following his four-hit performance on Monday night.

Note: The Angels activated infielder Maicer Izturis from the disabled list and optioned right-hander Darren O'Day to Triple-A Salt Lake.

... The White Sox, who lead the AL with 45 home runs, are 0-10 when they don't hit one.